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Anti-inflammatory effects of rosmarinic acid

(1) Anti-nephritis effect: Rosmarinic acid can inhibit the proliferation of mesangial cells and glomerular expansion.

(2) Anti-hepatitis effect: Rosmarinic acid can alleviate lipopolysaccharide (LPS)-induced liver damage and significantly inhibit the increase of plasma transaminase levels, which proves that the hepatoprotective effect of rosmarinic acid is by removing or reducing superoxide. or oxidized nitrite rather than by inhibiting TNF-α.

(3) Anti-pneumonic effect: Rosmarinic acid inhibits diesel exhaust particulate-induced neutrophil retention and lung injury characterized by interstitial edema.

(4) Anti-arthritis effect: Rosmarinic acid can inhibit collagen-induced arthritis and significantly reduce the number of arthritis and affected joints.

(5) Anti-periodontitis effect: Rosmarinic acid can inhibit the formation of bacterial plaque, thereby preventing chronic gingivitis.

(6) Anti-dermatitis effect: Rosmarinic acid has a relieving effect on atopic dermatitis, also known as atopic eczema or atopic eczema.

Antiviral effects of rosmarinic acid:

(1) Anti-herpes virus: rosmarinic acid shows special activity on type I and type II herpes simplex virus, and is an effective ingredient for controlling herpes disease. , but also rapidly combined with the viral coat protein, thereby inactivating the virus.

(2) Anti-HIV: Rosmarinic acid can inhibit the activity of HIV-1 (human immunodeficiency virus 1) integrase.

(3) Anti-encephalitis virus: Rosmarinic acid can reduce the mortality rate of mice with Japanese encephalitis virus, significantly reduce the viral load, and make the virus difficult to spread.

Anticancer and antitumor effects of rosmarinic acid: rosmarinic acid inhibits the expression of CCL11 and CCR3 by inhibiting the activity of β-kinase and the activation of related genes by nuclear factor kappa B, so as to achieve the purpose of antitumor.

Anti-allergic effects of rosmarinic acid: Rosmarinic acid inhibits allergic inflammation induced by microallergens.

Antioxidant effect of rosmarinic acid: Rosmarinic acid has good free radical scavenging and antioxidant effects.

Antithrombotic and antiplatelet aggregation effects of rosmarinic acid: Rosmarinic acid can inhibit the formation of malondialdehyde in human platelets in vitro, and its IC50 value is 3.37nmol/L, indicating that rosmarinic acid has antiplatelet aggregation activity.

Antidepressant effects of rosmarinic acid:

Anti-radiation and anti-ultraviolet effect of rosmarinic acid: Rosmarinic acid can be used as a photoprotectant to play the role of anti-radiation and anti-ultraviolet.

Other effects of rosmarinic acid:

(1) Stabilizing effect on color (2) Inhibiting effect on hyaluronidase (3) Inhibiting effect on xanthine oxidase (4) Protecting liver (5) Inhibition of angiogenesis (6) Prevention of arteriosclerosis (7) Prevention of memory impairment (8) Use as cosmetics

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